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KMID : 0365819710110020091
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Journal of Pusan Medical College
1971 Volume.11 No. 2 p.91 ~ p.97
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An Experimental Study on the Diagnosis of Rejection of Renal Homograft Using ^(131)I-Hippuran Renal Distribution Ratio
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Abstract
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An experimental study was made on the 131I-Hippuran renal distribution ratio in 39, mongrel dogs consisting of groups with normal, autotransplanted and homotransplanted kidneys for the evaluation of the rejection reaction in transplanted kidney.
The results were as follows:
1. Radioisotope 131I-Hippuran renal distribution ratio was decreased slightly in autotransplanted kidney and markedly in homotransplanted kidney as compared to that of normal control. And in the kidney of Imuran treated homotransplanted group, radioisotope tail-Hippuran renal distribution ratio was decreased moderately.
2. The degree of radioisotope 131I-Hippuran renal distribution ratio reduction of the transplanted
kidney was found to be generally consistent with that of rejection reaction.
3. It can be concluded that radioisotope 131I-Hippuran renal distribution ratio is more valuable than
the renal radioactivity count(cpm) or renography for the evaluation of the rejection reaction in transplanetd kidney.
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